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Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines

Autophagy represents an alternative tumor-suppressing mechanism that overcomes the dramatic resistance of malignant gliomas to radiotherapy and proapoptotic-related chemotherapy. This study reports that valproic acid (VPA), a widely used anti-epilepsy drug, induces autophagy in glioma cells. Autopha...

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Autores principales: Fu, Jun, Shao, Cui-Jie, Chen, Fu-Rong, Ng, Ho-Keung, Chen, Zhong-Ping
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940599/
https://ncbi.nlm.nih.gov/pubmed/20308311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop005
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