O(6)-methylguanine DNA-methyltransferase methylation status can change between first surgery for newly diagnosed glioblastoma and second surgery for recurrence: clinical implications

O(6)-methylguanine DNA-methyltransferase (MGMT) promoter methylation status is a prognostic factor in newly diagnosed glioblastoma patients. However, it is not yet clear whether, and if so how, MGMT methylation status may change. Moreover, it is unknown whether the prognostic role of this epigenetic...

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Detalhes bibliográficos
Main Authors: Brandes, Alba A., Franceschi, Enrico, Tosoni, Alicia, Bartolini, Stefania, Bacci, Antonella, Agati, Raffaele, Ghimenton, Claudio, Turazzi, Sergio, Talacchi, Andrea, Skrap, Miran, Marucci, Gianluca, Volpin, Lorenzo, Morandi, Luca, Pizzolitto, Stefano, Gardiman, Marina, Andreoli, Alvaro, Calbucci, Fabio, Ermani, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940594/
https://ncbi.nlm.nih.gov/pubmed/20167816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop050
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