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Human Gene Targeting Favors Insertions Over Deletions
Gene targeting is a powerful technique for manipulating the human genome, but few studies have directly compared the targeting frequencies of various types of vector constructs. Here we show that similar targeting constructs are able to insert nucleotides at the homologous chromosomal target locus m...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Mary Ann Liebert, Inc.
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940567/ https://ncbi.nlm.nih.gov/pubmed/18680404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2008.061 |
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