Cholecystokinin Is Up-Regulated in Obese Mouse Islets and Expands β-Cell Mass by Increasing β-Cell Survival

An absolute or functional deficit in β-cell mass is a key factor in the pathogenesis of diabetes. We model obesity-driven β-cell mass expansion by studying the diabetes-resistant C57BL/6-Leptin(ob/ob) mouse. We previously reported that cholecystokinin (Cck) was the most up-regulated gene in obese pa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lavine, Jeremy A., Raess, Philipp W., Stapleton, Donald S., Rabaglia, Mary E., Suhonen, Joshua I., Schueler, Kathryn L., Koltes, James E., Dawson, John A., Yandell, Brian S., Samuelson, Linda C., Beinfeld, Margery C., Davis, Dawn Belt, Hellerstein, Marc K., Keller, Mark P., Attie, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940525/
https://ncbi.nlm.nih.gov/pubmed/20534724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0233
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados