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Large Litter Rearing Enhances Leptin Sensitivity and Protects Selectively Bred Diet-Induced Obese Rats from Becoming Obese

Because rearing rats in large litters (LLs) protects them from becoming obese, we postulated that LL rearing would protect rats selectively bred to develop diet-induced obesity (DIO) from becoming obese by overcoming their inborn central leptin resistance. Male and female DIO rats were raised in nor...

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Autori principali: Patterson, Christa M., Bouret, Sebastien G., Park, Sunny, Irani, Boman G., Dunn-Meynell, Ambrose A., Levin, Barry E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940492/
https://ncbi.nlm.nih.gov/pubmed/20668022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0401
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