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17β-Estradiol Rapidly Increases K(ATP) Activity in GnRH via a Protein Kinase Signaling Pathway

17β-Estradiol (E2) both inhibits and excites GnRH neurons via presynaptic as well as postsynaptic mechanisms. Although it has been demonstrated that E2 can alter the excitability of GnRH neurons via direct actions, the intracellular signaling cascades mediating these actions are not well understood....

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Detalhes bibliográficos
Main Authors: Zhang, Chunguang, Kelly, Martin J., Rønnekleiv, Oline K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940490/
https://ncbi.nlm.nih.gov/pubmed/20660067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0177
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