Systemic Delivery of Bioactive Glucagon-Like Peptide 1 after Adenoviral-Mediated Gene Transfer in the Murine Salivary Gland

An adenoviral (Ad) vector that expresses bioactive glucagon-like peptide 1 (GLP-1) was generated, and its effectiveness at modulating glucose homeostasis was evaluated after transduction of murine salivary glands. The construct was engineered with the signal sequence of mouse GH to direct the peptid...

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Bibliografiske detaljer
Main Authors: Voutetakis, Antonis, Cotrim, Ana P., Rowzee, Anne, Zheng, Changyu, Rathod, Trushar, Yanik, Tulin, Loh, Y. Peng, Baum, Bruce J., Cawley, Niamh X.
Format: Artigo
Sprog:Inglês
Udgivet: The Endocrine Society 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940489/
https://ncbi.nlm.nih.gov/pubmed/20610567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0193
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