Luteinizing Hormone Receptor-Stimulated Progesterone Production by Preovulatory Granulosa Cells Requires Protein Kinase A-Dependent Activation/Dephosphorylation of the Actin Dynamizing Protein Cofilin

Activation of the LH receptor (LHR) on preovulatory granulosa cells stimulates the cAMP/protein kinase A (PKA) pathway to regulate expression of genes required for ovulation and luteinization. LHR signaling also initiates rearrangement of the actin cytoskeleton. Because disruption of the actin cytos...

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Main Authors: Karlsson, Amelia B., Maizels, Evelyn T., Flynn, Maxfield P., Jones, Jonathan C., Shelden, Eric A., Bamburg, James R., Hunzicker-Dunn, Mary
Format: Artigo
Jezik:Inglês
Izdano: The Endocrine Society 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940477/
https://ncbi.nlm.nih.gov/pubmed/20610540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0487
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