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Suppression of Radiation-Induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. III. Candidate Gene Analysis Identifies a Role for Fas in the Attenuation of X-ray–Induced Apoptosis

Germ cell apoptosis directly induced by x-radiation (x-ray) exposure is stage specific, with a higher incidence in stage II/III seminiferous tubules. A priming exposure to the Sertoli cell toxicant 2,5-hexanedione (HD) results in a marked reduction in x-ray–induced germ cell apoptosis in these affec...

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Detalhes bibliográficos
Main Authors: Campion, Sarah N., Sandrof, Moses A., Yamasaki, Hideki, Boekelheide, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940406/
https://ncbi.nlm.nih.gov/pubmed/20616204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq205
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