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Suppression of Radiation-Induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. II. Gene Array Analysis Reveals Adaptive Changes in Cell Cycle and Cell Death Pathways

Sertoli cells are essential for testicular germ cell maintenance and survival. We made the unexpected observation that x-radiation (x-ray)–induced germ cell loss is attenuated by co-exposure with the Sertoli cell toxicant 2,5-hexanedione (HD). The mechanisms underlying this attenuation of germ cell...

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Bibliografske podrobnosti
Main Authors: Campion, Sarah N., Houseman, E. Andres, Sandrof, Moses A., Hensley, Janan B., Sui, Yunxia, Gaido, Kevin W., Wu, Zhijin, Boekelheide, Kim
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940405/
https://ncbi.nlm.nih.gov/pubmed/20616210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq204
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