Suppression of Radiation-Induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. II. Gene Array Analysis Reveals Adaptive Changes in Cell Cycle and Cell Death Pathways

Sertoli cells are essential for testicular germ cell maintenance and survival. We made the unexpected observation that x-radiation (x-ray)–induced germ cell loss is attenuated by co-exposure with the Sertoli cell toxicant 2,5-hexanedione (HD). The mechanisms underlying this attenuation of germ cell...

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Detalhes bibliográficos
Main Authors: Campion, Sarah N., Houseman, E. Andres, Sandrof, Moses A., Hensley, Janan B., Sui, Yunxia, Gaido, Kevin W., Wu, Zhijin, Boekelheide, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Reproductive and Developmental Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940405/
https://ncbi.nlm.nih.gov/pubmed/20616210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq204
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