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Suppression of Radiation-Induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. II. Gene Array Analysis Reveals Adaptive Changes in Cell Cycle and Cell Death Pathways
Sertoli cells are essential for testicular germ cell maintenance and survival. We made the unexpected observation that x-radiation (x-ray)–induced germ cell loss is attenuated by co-exposure with the Sertoli cell toxicant 2,5-hexanedione (HD). The mechanisms underlying this attenuation of germ cell...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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Oxford University Press
2010
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Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940405/ https://ncbi.nlm.nih.gov/pubmed/20616210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq204 |
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