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Suppression of Radiation-Induced Testicular Germ Cell Apoptosis by 2,5-Hexanedione Pretreatment. II. Gene Array Analysis Reveals Adaptive Changes in Cell Cycle and Cell Death Pathways

Sertoli cells are essential for testicular germ cell maintenance and survival. We made the unexpected observation that x-radiation (x-ray)–induced germ cell loss is attenuated by co-exposure with the Sertoli cell toxicant 2,5-hexanedione (HD). The mechanisms underlying this attenuation of germ cell...

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Main Authors: Campion, Sarah N., Houseman, E. Andres, Sandrof, Moses A., Hensley, Janan B., Sui, Yunxia, Gaido, Kevin W., Wu, Zhijin, Boekelheide, Kim
格式: Artigo
語言:Inglês
出版: Oxford University Press 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940405/
https://ncbi.nlm.nih.gov/pubmed/20616210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq204
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