Glucarpidase, Leucovorin, and Thymidine for High-Dose Methotrexate-Induced Renal Dysfunction: Clinical and Pharmacologic Factors Affecting Outcome

PURPOSE: To assess the role of the recombinant bacterial enzyme, glucarpidase (carboxypeptidase-G(2)), leucovorin, and thymidine in the management and outcome of patients with high-dose methotrexate (HDMTX) –induced nephrotoxicity. METHODS: Patients with HDMTX-induced nephrotoxicity received one to...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Widemann, Brigitte C., Balis, Frank M., Kim, AeRang, Boron, Matthew, Jayaprakash, Nalini, Shalabi, Aiman, O'Brien, Michelle, Eby, Michelle, Cole, Diane E., Murphy, Robert F., Fox, Elizabeth, Ivy, Percy, Adamson, Peter C.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Clinical Oncology 2010
נושאים:
Original Reports
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940396/
https://ncbi.nlm.nih.gov/pubmed/20679598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.25.4540
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