Glucarpidase, Leucovorin, and Thymidine for High-Dose Methotrexate-Induced Renal Dysfunction: Clinical and Pharmacologic Factors Affecting Outcome

PURPOSE: To assess the role of the recombinant bacterial enzyme, glucarpidase (carboxypeptidase-G(2)), leucovorin, and thymidine in the management and outcome of patients with high-dose methotrexate (HDMTX) –induced nephrotoxicity. METHODS: Patients with HDMTX-induced nephrotoxicity received one to...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Widemann, Brigitte C., Balis, Frank M., Kim, AeRang, Boron, Matthew, Jayaprakash, Nalini, Shalabi, Aiman, O'Brien, Michelle, Eby, Michelle, Cole, Diane E., Murphy, Robert F., Fox, Elizabeth, Ivy, Percy, Adamson, Peter C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Clinical Oncology 2010
Aiheet:
Original Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940396/
https://ncbi.nlm.nih.gov/pubmed/20679598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.25.4540
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