Consensus Guideline for Use of Glucarpidase in Patients with High‐Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance

Acute kidney injury due to high‐dose methotrexate (HDMTX) is a serious, life‐threatening toxicity that can occur in pediatric and adult patients. Glucarpidase is a treatment approved by the Food and Drug Administration for high methotrexate concentrations in the context of kidney dysfunction, but th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncologist
Main Authors: Ramsey, Laura B., Balis, Frank M., O'Brien, Maureen M., Schmiegelow, Kjeld, Pauley, Jennifer L., Bleyer, Archie, Widemann, Brigitte C., Askenazi, David, Bergeron, Sharon, Shirali, Anushree, Schwartz, Stefan, Vinks, Alexander A., Heldrup, Jesper
Format: Artigo
Jezik:Inglês
Izdano: AlphaMed Press 2017
Teme:
New Drug Development and Clinical Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5759822/
https://ncbi.nlm.nih.gov/pubmed/29079637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0243
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