Consensus Guideline for Use of Glucarpidase in Patients with High‐Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance

Acute kidney injury due to high‐dose methotrexate (HDMTX) is a serious, life‐threatening toxicity that can occur in pediatric and adult patients. Glucarpidase is a treatment approved by the Food and Drug Administration for high methotrexate concentrations in the context of kidney dysfunction, but th...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Ramsey, Laura B., Balis, Frank M., O'Brien, Maureen M., Schmiegelow, Kjeld, Pauley, Jennifer L., Bleyer, Archie, Widemann, Brigitte C., Askenazi, David, Bergeron, Sharon, Shirali, Anushree, Schwartz, Stefan, Vinks, Alexander A., Heldrup, Jesper
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2017
Assuntos:
New Drug Development and Clinical Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5759822/
https://ncbi.nlm.nih.gov/pubmed/29079637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0243
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