Glucarpidase, Leucovorin, and Thymidine for High-Dose Methotrexate-Induced Renal Dysfunction: Clinical and Pharmacologic Factors Affecting Outcome

PURPOSE: To assess the role of the recombinant bacterial enzyme, glucarpidase (carboxypeptidase-G(2)), leucovorin, and thymidine in the management and outcome of patients with high-dose methotrexate (HDMTX) –induced nephrotoxicity. METHODS: Patients with HDMTX-induced nephrotoxicity received one to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Widemann, Brigitte C., Balis, Frank M., Kim, AeRang, Boron, Matthew, Jayaprakash, Nalini, Shalabi, Aiman, O'Brien, Michelle, Eby, Michelle, Cole, Diane E., Murphy, Robert F., Fox, Elizabeth, Ivy, Percy, Adamson, Peter C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Clinical Oncology 2010
Gaiak:
Original Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940396/
https://ncbi.nlm.nih.gov/pubmed/20679598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.25.4540
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