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Single-molecule dynamics of gating in a neurotransmitter transporter homolog

Neurotransmitter:Na(+) symporters (NSS) remove neurotransmitters from the synapse in a reuptake process driven by the Na(+) gradient. Drugs that interfere with this reuptake mechanism, such as cocaine and antidepressants, profoundly influence behavior and mood. In order to probe the nature of confor...

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Detalhes bibliográficos
Main Authors: Zhao, Yongfang, Terry, Daniel, Shi, Lei, Weinstein, Harel, Blanchard, Scott C., Javitch, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940119/
https://ncbi.nlm.nih.gov/pubmed/20463731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09057
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