Deficiency of the Metalloproteinase-Disintegrin ADAM8 Is Associated with Thymic Hyper-Cellularity

BACKGROUND: Thymopoiesis requires thymocyte-stroma interactions and proteases that promote cell migration by degrading extracellular matrix and releasing essential cytokines and chemokines. A role for several members of the A Disintegrin and Metalloprotease (ADAM) family in T cell development has be...

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Autores principales: Gossens, Klaus, Naus, Silvia, Holländer, Georg A., Ziltener, Hermann J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939894/
https://ncbi.nlm.nih.gov/pubmed/20856819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012766
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