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Role of CD38, a Cyclic ADP-Ribosylcyclase, in Morphine Antinociception and Tolerance

Our previous studies have demonstrated that an increase in intracellular levels of Ca(2+) in neurons is an important component of both the antinociception produced by morphine and morphine's tolerance. The present study tested the hypothesis that the Ca(2+) signaling second messenger, cyclic AD...

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Detalhes bibliográficos
Main Authors: Hull, Lynn C., Rabender, Christopher, Gabra, Bichoy H., Zhang, Fan, Li, Pin-Lan, Dewey, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939677/
https://ncbi.nlm.nih.gov/pubmed/20551293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.169243
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