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Role of Sphingolipid Mediator Ceramide in Obesity and Renal Injury in Mice Fed a High-Fat Diet

The present study tested a hypothesis that excess accumulation of sphingolipid, ceramide, its metabolites, or a combination contributes to the development of obesity and associated kidney damage. Liquid chromatography/mass spectrometry analysis demonstrated that C57BL/6J mice on the high-fat diet (H...

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Detalhes bibliográficos
Main Authors: Boini, Krishna M., Zhang, Chun, Xia, Min, Poklis, Justin L., Li, Pin-Lan
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939660/
https://ncbi.nlm.nih.gov/pubmed/20543095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.168815
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