Augmented inhibition of angiogenesis by combination of HER2 antibody chA21 and trastuzumab in human ovarian carcinoma xenograft

BACKGROUND: chA21 is a novel tumor-inhibitory antibody which recognized subdomain I of HER2 extracellular domain with an epitope distinct from other HER2 antibodies. Previously, we demonstrated that chA21 inhibits human ovarian carcinoma cell line SKOV-3 growth in vitro and in vivo study. In this st...

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Detalhes bibliográficos
Main Authors: Zhang, Anli, Shen, Guodong, Zhao, Ting, Zhang, Guihong, Liu, Jing, Song, Lihua, Wei, Wei, Bing, Ling, Wu, Zhengsheng, Wu, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939608/
https://ncbi.nlm.nih.gov/pubmed/20723224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-3-20
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