Anti-HER-2 engineering antibody ChA21 inhibits growth and induces apoptosis of SK-OV-3 cells

BACKGROUND AND AIMS: Anti-HER-2 antibodies targeting distinct epitopes have different biological functions on cancer cells. In a previous study, we demonstrated that anti-HER-2 engineering antibody ChA21 was able to bind to subdomain I of HER-2 extracellular domain. In this study, The effects of ChA...

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Autori principali: Zhang, AnLi, Xue, Hua, Ling, XiaoGuang, Gao, Yi, Yang, Feng, Cheng, LianSheng, Liu, Jing, Wu, Qiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846882/
https://ncbi.nlm.nih.gov/pubmed/20214830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-23
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