The Effect of Allosteric Modulators on the Kinetics of Agonist-G Protein-Coupled Receptor Interactions in Single Living Cells

Allosteric binding sites on adenosine -A(1) and -A(3) receptors represent attractive therapeutic targets for amplifying, in a spatially and temporally selective manner, the tissue protective actions of endogenous adenosine. This study has directly quantified the kinetics of agonist/G protein-coupled...

Full description

Saved in:
Bibliographic Details
Main Authors: May, Lauren T., Self, Tim J., Briddon, Stephen J., Hill, Stephen J.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2010
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939483/
https://ncbi.nlm.nih.gov/pubmed/20571079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.064493
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items