Posttranslational Regulation of Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) in Mouse PTEN Null Prostate Cancer Cells: Enhanced Surface Expression and Differential O-Glycosylation of MT1-MMP

Membrane type 1 (MT1)-matrix metalloproteinase (MT1-MMP) is a membrane-tethered MMP that has been shown to play a key role in promoting cancer cell invasion. MT1-MMP is highly expressed in bone metastasis of prostate cancer (PC) patients and promotes intraosseous tumor growth of PC cells in mice. Th...

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Main Authors: Kim, Seaho, Huang, Wei, Mottillo, Emilio P., Sohail, Anjum, Ham, Yoon-Ah, Conley-LaComb, M. Katie, Kim, Chong Jai, Tzivion, Guri, Kim, Hyeong-Reh Choi, Wang, Shihua, Chen, Yong Q., Fridman, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939279/
https://ncbi.nlm.nih.gov/pubmed/20620173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2010.06.011
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