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Inhibition of deoxyribonucleic acid gyrase: effects on nucleic acid synthesis and cell division in Escherichia coli K-12.

Mutants of Escherichia coli resistant to the antibiotic clorobiocin are also coumermycin resistant, and the mutation to resistance in at least one mutant was mapped near gyrB. We conclude, therefore, that clorobiocin inhibits deoxyribonucleic acid gyrase, and the drug was used to probe the role of t...

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Autors principals: Fairweather, N F, Orr, E, Holland, I B
Format: Artigo
Idioma:Inglês
Publicat: 1980
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC293920/
https://ncbi.nlm.nih.gov/pubmed/6154685
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