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Inhibition of deoxyribonucleic acid gyrase: effects on nucleic acid synthesis and cell division in Escherichia coli K-12.

Mutants of Escherichia coli resistant to the antibiotic clorobiocin are also coumermycin resistant, and the mutation to resistance in at least one mutant was mapped near gyrB. We conclude, therefore, that clorobiocin inhibits deoxyribonucleic acid gyrase, and the drug was used to probe the role of t...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Fairweather, N F, Orr, E, Holland, I B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293920/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6154685/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.142.1.153-161.1980
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