alpha-Fucose-mediated binding and degradation of tissue-type plasminogen activator by HepG2 cells.

The glycoprotein tissue-type plasminogen activator (t-PA) is subject to hepatic clearance in humans. Here, the interaction of t-PA with a well-differentiated hepatoma cell line (HepG2) was examined. Suspended HepG2 cells bound 125I-t-PA in a specific, saturable, and reversible fashion through a Ca(2...

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Bibliografische gegevens

Gepubliceerd in:	J Clin Invest
Hoofdauteurs:	Hajjar, K A, Reynolds, C M
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Clinical Investigation 1994
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8113404/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117023
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