alpha-Fucose-mediated binding and degradation of tissue-type plasminogen activator by HepG2 cells.
The glycoprotein tissue-type plasminogen activator (t-PA) is subject to hepatic clearance in humans. Here, the interaction of t-PA with a well-differentiated hepatoma cell line (HepG2) was examined. Suspended HepG2 cells bound 125I-t-PA in a specific, saturable, and reversible fashion through a Ca(2...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1994
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8113404/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117023 |
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