Lipopolysaccharide (LPS)-binding protein and soluble CD14 function as accessory molecules for LPS-induced changes in endothelial barrier function, in vitro.

Bacterial LPS induces endothelial cell (EC) injury both in vivo and in vitro. We studied the effect of Escherichia coli 0111:B4 LPS on movement of 14C-BSA across bovine pulmonary artery EC monolayers. In the presence of serum, a 6-h LPS exposure augmented (P < 0.001) transendothelial 14C-BSA flux co...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Goldblum, S E, Brann, T W, Ding, X, Pugin, J, Tobias, P S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509346/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117022
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