Lipopolysaccharide (LPS)-binding protein and soluble CD14 function as accessory molecules for LPS-induced changes in endothelial barrier function, in vitro.

Bacterial LPS induces endothelial cell (EC) injury both in vivo and in vitro. We studied the effect of Escherichia coli 0111:B4 LPS on movement of 14C-BSA across bovine pulmonary artery EC monolayers. In the presence of serum, a 6-h LPS exposure augmented (P < 0.001) transendothelial 14C-BSA flux...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Goldblum, S E, Brann, T W, Ding, X, Pugin, J, Tobias, P S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293903/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509346/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117022
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