Endothelin (ET)-3 stimulates cyclic guanosine 3',5'-monophosphate production via ETB receptor by producing nitric oxide in isolated rat glomerulus, and in cultured rat mesangial cells.

We investigated the effects of endothelins on receptor-mediated cyclic nucleotide metabolism in rat glomerulus, inner medullary collecting duct (IMCD), and also in cultured rat glomerular mesangial cells. Endothelin (ET)-3 dose-dependently stimulated cGMP accumulation in glomerulus, which was higher...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Owada, A, Tomita, K, Terada, Y, Sakamoto, H, Nonoguchi, H, Marumo, F
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293878/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509343/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117007
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!