Involvement of beta 2-microglobulin modified with advanced glycation end products in the pathogenesis of hemodialysis-associated amyloidosis. Induction of human monocyte chemotaxis and macrophage secretion of tumor necrosis factor-alpha and interleukin-1.

beta 2-Microglobulin (beta 2M) is a major constituent of amyloid fibrils in hemodialysis-associated amyloidosis (HAA), a complication of long-term hemodialysis. However, the pathological role of beta 2M in HAA remains to be determined. Recently, we demonstrated that beta 2M in the amyloid deposits o...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Miyata, T, Inagi, R, Iida, Y, Sato, M, Yamada, N, Oda, O, Maeda, K, Seo, H
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1994
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293873/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8113390/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117002
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