TLR4 Promotes Fibrosis but Attenuates Tubular Damage in Progressive Renal Injury

Toll-like receptors (TLRs) can orchestrate an inflammatory response upon activation by pathogen-associated motifs and release of endogenous stress ligands during tissue injury. The kidney constitutively expresses most TLRs, including TLR4. The function of TLR4 during the inflammation, tubular atroph...

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Detalhes bibliográficos
Main Authors: Pulskens, Wilco P., Rampanelli, Elena, Teske, Gwendoline J., Butter, Loes M., Claessen, Nike, Luirink, Ilse K., van der Poll, Tom, Florquin, Sandrine, Leemans, Jaklien C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938595/
https://ncbi.nlm.nih.gov/pubmed/20595685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009070722
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