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Structural insights into mRNA recognition from a PIWI domain – siRNA guide complex
RNA interference (RNAi) and related RNA silencing phenomena use short antisense guide RNA molecules to repress expression of target genes1,2. Argonaute proteins3, containing N-terminal PAZ domains and C-terminal PIWI domains, are core components of these mechanisms. Here we present the crystal struc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938470/ https://ncbi.nlm.nih.gov/pubmed/15800628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03462 |
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