Structural Biology of DNA Repair: Spatial Organisation of the Multicomponent Complexes of Nonhomologous End Joining

Nonhomologous end joining (NHEJ) plays a major role in double-strand break DNA repair, which involves a series of steps mediated by multiprotein complexes. A ring-shaped Ku70/Ku80 heterodimer forms first at broken DNA ends, DNA-dependent protein kinase catalytic subunit (DNA-PKcs) binds to mediate s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Ochi, Takashi, Sibanda, Bancinyane Lynn, Wu, Qian, Chirgadze, Dimitri Y., Bolanos-Garcia, Victor M., Blundell, Tom L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: SAGE-Hindawi Access to Research 2010
Aiheet:
Review Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938450/
https://ncbi.nlm.nih.gov/pubmed/20862368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/621695
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