Cerebral atrophy as outcome measure in short-term phase 2 clinical trials in multiple sclerosis

INTRODUCTION: Cerebral atrophy is a compound measure of the neurodegenerative component of multiple sclerosis (MS) and a conceivable outcome measure for clinical trials monitoring the effect of neuroprotective agents. In this study, we evaluate the rate of cerebral atrophy in a 6-month period, inves...

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Bibliografiske detaljer
Main Authors: van den Elskamp, I. J., Boden, B., Dattola, V., Knol, D. L., Filippi, M., Kappos, L., Fazekas, F., Wagner, K., Pohl, C., Sandbrink, R., Polman, C. H., Uitdehaag, B. M. J., Barkhof, F.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2010
Fag:
Diagnostic Neuroradiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938443/
https://ncbi.nlm.nih.gov/pubmed/20049424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00234-009-0645-1
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