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Inhibition of Melanoma Growth by Subcutaneous Administration of hTERTC27 Viral Cocktail in C57BL/6 Mice

BACKGROUND: hTERTC27 is a 27 kDa C-terminal polypeptide of human telomerase reverse transcriptase that has previously been shown to reduce tumorigenicity of HeLa cells and suppress growth of xenografted glioblastoma in nude mice. Although ectopic expression of hTERTC27 upregulated genes that are inv...

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Bibliografiske detaljer
Main Authors: Huo, Longfei, Yao, Hong, Wang, Xicai, Wong, Gee Wan, Kung, Hsiang-fu, Lin, Marie C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938346/
https://ncbi.nlm.nih.gov/pubmed/20856939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012705
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