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Concentration-dependent Toxicity after Subcutaneous Administration of Meloxicam to C57BL/6N Mice (Mus musculus)

Studies using the Mouse Grimace Scale have shown that for many NSAID, including meloxicam, minimal doses of at least 20 mg/kg may be necessary to achieve adequate peri- and postoperative analgesia in mice. However, more data are needed to determine whether such NSAID doses exceed the threshold for g...

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Detalhes bibliográficos
Publicado no:J Am Assoc Lab Anim Sci
Main Authors: Sarfaty, Anna E, Zeiss, Caroline J, Willis, Amy D, Harris, Jorgen M, Smith, Peter C
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Laboratory Animal Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926403/
https://ncbi.nlm.nih.gov/pubmed/31540585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.30802/AALAS-JAALAS-19-000037
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