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Epigenetic Drugs Can Stimulate Metastasis through Enhanced Expression of the Pro-Metastatic Ezrin Gene

Ezrin has been reported to be upregulated in many tumors and to participate in metastatic progression. No study has addressed epigenetic modification in the regulation of Ezrin gene expression, the importance of which is unknown. Here, we report that highly metastatic rhabdomyosarcoma (RMS) cells wi...

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Autors principals: Yu, Yanlin, Zeng, Pingyao, Xiong, Jingbo, Liu, Ziyang, Berger, Shelley L., Merlino, Glenn
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938331/
https://ncbi.nlm.nih.gov/pubmed/20856924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012710
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