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The Kunitz-3 domain of TFPI-α is required for protein S–dependent enhancement of factor Xa inhibition
Protein S (PS) enhances the inhibition of factor Xa (FXa) by tissue factor pathway inhibitor-α (TFPI-α) in the presence of Ca(2+) and phospholipids. Altered forms of recombinant TFPI-α were used to determine the structures within TFPI-α that may be involved in this PS-dependent effect. Wild-type TFP...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938241/ https://ncbi.nlm.nih.gov/pubmed/20479289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-246686 |
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