Human ADA3 regulates RARα transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket

The alternation/deficiency in activation-3 (ADA3) is an essential component of the human p300/CBP-associated factor (PCAF) and yeast Spt-Ada-Gcn5-acetyltransferase (SAGA) histone acetyltransferase complexes. These complexes facilitate transactivation of target genes by association with transcription...

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Hlavní autoři: Li, Chia-Wei, Ai, Ni, Dinh, Gia Khanh, Welsh, William J., Chen, J. Don
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938230/
https://ncbi.nlm.nih.gov/pubmed/20413580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq269
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