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Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins
E6 viral oncoproteins are key players in epithelial tumors induced by Papillomaviruses in vertebrates, including cervical cancer in humans. E6 proteins target many host proteins by specifically interacting with acidic LxxLL motifs. Here, we solved the crystal structures of Bovine (BPV1) and Human (H...
Bewaard in:
| Hoofdauteurs: | , , , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899395/ https://ncbi.nlm.nih.gov/pubmed/23393263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1229934 |
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