Single molecule analysis of combinatorial splicing

Alternative splicing creates diverse mRNA isoforms from single genes and thereby enhances complexity of transcript structure and of gene function. We describe a method called spliceotyping, which translates combinatorial mRNA splicing patterns along transcripts into a library of binary strings of nu...

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Bibliographic Details
Main Authors: Conze, Tim, Göransson, Jenny, Razzaghian, Hamid Reza, Ericsson, Olle, Öberg, Daniel, Akusjärvi, Göran, Landegren, Ulf, Nilsson, Mats
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938221/
https://ncbi.nlm.nih.gov/pubmed/20587504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq581
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