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Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells—identification of a novel androgen response element
Cyclin D1 gene (CCND1) is a critical mitogen-regulated cell-cycle control element whose transcriptional modulation plays a crucial role in breast cancer growth and progression. Here we demonstrate that the non-aromatizable androgen 5-α-dihydrotestosterone (DHT) inhibits endogenous cyclin D1 expressi...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938215/ https://ncbi.nlm.nih.gov/pubmed/20421209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq278 |
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