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Transcriptional properties of human NANOG1 and NANOG2 in acute leukemic cells

Transcripts of NANOG and OCT4 have been recently identified in human t(4;11) leukemia and in a model system expressing both t(4;11) fusion proteins. Moreover, downstream target genes of NANOG/OCT4/SOX2 were shown to be transcriptionally activated. However, the NANOG1 gene belongs to a gene family, i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Eberle, Irina, Pless, Birgit, Braun, Miriam, Dingermann, Theo, Marschalek, Rolf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938211/
https://ncbi.nlm.nih.gov/pubmed/20427424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq307
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