High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

B-cell receptor (BCR) diversity is achieved centrally by rearrangement of Variable, Diversity, and Joining genes, and peripherally by somatic hypermutation and class-switching of the rearranged genes. Peripheral B-cell populations are subject to both negative and positive selection events in the cou...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Wu, Yu-Chang, Kipling, David, Leong, Hui Sun, Martin, Victoria, Ademokun, Alexander A., Dunn-Walters, Deborah K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938129/
https://ncbi.nlm.nih.gov/pubmed/20457872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-275859
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky