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Quantitative Proteomics Analysis of the Nuclear Fraction of Human CD4(+) Cells in the Early Phases of IL-4-induced Th2 Differentiation
We used stable isotope labeling with 4-plex iTRAQ (isobaric tags for relative and absolute quantification) reagents and LC-MS/MS to investigate proteomic changes in the nucleus of activated human CD4(+) cells during the early stages of Th2 cell differentiation. The effects of IL-4 stimulation upon a...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938108/ https://ncbi.nlm.nih.gov/pubmed/20467038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900483-MCP200 |
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