A Novel, In-solution Separation of Endogenous Cardiac Sarcomeric Proteins and Identification of Distinct Charged Variants of Regulatory Light Chain

The molecular conformation of the cardiac myosin motor is modulated by intermolecular interactions among the heavy chain, the light chains, myosin binding protein-C, and titin and is governed by post-translational modifications (PTMs). In-gel digestion followed by LC/MS/MS has classically been appli...

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Bibliografische gegevens
Hoofdauteurs: Scruggs, Sarah B., Reisdorph, Rick, Armstrong, Mike L., Warren, Chad M., Reisdorph, Nichole, Solaro, R. John, Buttrick, Peter M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2010
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938104/
https://ncbi.nlm.nih.gov/pubmed/20445002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.000075
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