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Probing Native Protein Structures by Chemical Cross-linking, Mass Spectrometry, and Bioinformatics

Chemical cross-linking of reactive groups in native proteins and protein complexes in combination with the identification of cross-linked sites by mass spectrometry has been in use for more than a decade. Recent advances in instrumentation, cross-linking protocols, and analysis software have led to...

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Detalles Bibliográficos
Main Authors: Leitner, Alexander, Walzthoeni, Thomas, Kahraman, Abdullah, Herzog, Franz, Rinner, Oliver, Beck, Martin, Aebersold, Ruedi
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938055/
https://ncbi.nlm.nih.gov/pubmed/20360032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.R000001-MCP201
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