A Conserved E7-derived Cytotoxic T Lymphocyte Epitope Expressed on Human Papillomavirus 16-transformed HLA-A2(+) Epithelial Cancers

Human Papillomavirus 16 (HPV-16) has been identified as the causative agent of 50% of cervical cancers and many other HPV-associated tumors. The transforming potential/tumor maintenance capacity of this high risk HPV is mediated by two viral oncoproteins, E6 and E7, making them attractive targets fo...

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Main Authors: Riemer, Angelika B., Keskin, Derin B., Zhang, Guanglan, Handley, Maris, Anderson, Karen S., Brusic, Vladimir, Reinhold, Bruce, Reinherz, Ellis L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937992/
https://ncbi.nlm.nih.gov/pubmed/20615877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.126722
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