Histone XH2AX Is Required for Xenopus Anterior Neural Development: CRITICAL ROLE OF THREONINE 16 PHOSPHORYLATION

A role for histone H2AX, one of the variants of the nucleosome core histone H2A, has been demonstrated in DNA repair, tumor suppression, apoptosis, and cell cycle checkpoint function. However, the physiological function and post-translational modification of histone H2AX during vertebrate developmen...

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Bibliografiske detaljer
Main Authors: Lee, Sung-Young, Lau, Andy T. Y., Jeong, Chul-Ho, Shim, Jung-Hyun, Kim, Hong-Gyum, Kim, Jaebong, Bode, Ann M., Dong, Zigang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937984/
https://ncbi.nlm.nih.gov/pubmed/20639511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127233
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